Accelerating machine learning recombinase reprogramming

Machine Learning


This webinar will be hosted live and available on demand.

Wednesday, September 24th, 2025
11:00am – 12:00pm ET

The future of gene editing relies on tools that are programmable, scalable, and adaptable to diverse disease contexts. Recombinases have emerged as promising solutions, but robust blends of experimental and computational strategies are required to optimize their performance.

SeamlessTX addresses this challenge with a unique platform that integrates large-scale orientation evolution and machine learning (ML)-driven models to predict recombinase variant activity and specificity. Twist gene fragments allow rapid verification of predicted variants and deploy them into evolutionary campaigns.

In this webinar brought by Twist Bioscience, Felix Lansing explores how SeamlessTX's data-driven approach accelerates the production of high-performance recombinases and expands the therapeutic potential of gene editing.

Topics covered:

  • Therapeutic potential of recombinases in the treatment of diseases
  • Applying ML workflows to accelerate the evolution of novel recombinases
  • How SeamlessTx reduces variant verification workflows from 7-9 days by using Twist Gene Fragments to power AI-driven engineering pipelines
Dr. Felix Lansing

Dr. Felix Lansing
Co-founder and Chief Technology Officer
SeamLessTX



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